Balancing the Evidence: Cancer and Dietary Fat references
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References from the Medical Literature:

  1. Bartsch, H; Nair, J; Owen, RW. Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers. Carcinogenesis.20:2209-18, 1999.
    • This review implicates a high intake of omega 6 polyunsaturated fatty acids in cancer of the breast, colon and possibly prostate and a protective effect of omega 3 polyunsaturated fatty acids. [abstract]
  2. Brawley, OW; Knopf, K; Thompson, I. The epidemiology of prostate cancer part II: the risk factors. Sem Urologic Onc.16:193-201. 1998.
    • This review suggests that the cause of prostate cancer is likely to be a combination of genetic and environmental factors. One of the environmental factors may be dietary fat. [abstract]
  3. Fradet, Y; Meyer, F; Bairati, I; Shadmani, R; Moore, L. Dietary fat and prostate cancer progression and survival. Eur Urology. 35:388-91, 1999.
    • A case control study that showed saturated fat consumption to be significantly associated with disease specific survival. A moderate reduction of its intake below 10% should reduce the risk of dying from prostate cancer. [abstract]
  4. Gogos, CA; Skoutelis, A; Kalfarentzos, F. The effects of lipids on the immune response of patients with cancer. J Nutr Health Aging. 4:172-5, 2000.
    • The review describes evidence for the beneficial effect of omega 3 fatty acids on cancer growth and metastasis. [abstract]
  5. Guthrie, N; Carroll, KK. Specific versus non-specific effects of dietary fat on carcinogenesis. Prog Lipid Res. 38:261-71, 1999.
    • This review describes the specific and nonspecific effects of dietary fat on carcinogenesis. The non specific effect increases the risk through achievement a of a positive energy balance leading to obesity. The specific effects, e.g. omega 3 fatty acids may be of value for the prevention or treatment of cancer. [abstract]
  6. Kolonel, LN; Nomura, AM; Cooney, RV. Dietary fat and prostate cancer: current status. J Natl Cancer Institute. 91:414-28, 1999.
    • Reviewers conclude that dietary fat may be related to prostate cancer risk, although the specific fat components responsible are not clear. [abstract]
  7. Lee, MM; Lin,SS. Dietary fat and breast cancer. Ann Rev Nutr 20:221-48, 2000.
    • Although epidemiological data supported dietary fat as a risk factor for breast cancer , data from case control studies and cohort studies have been equivocal and do not support a strong positive association. [abstract]
  8. Willett, WC. Diet and cancer. Oncologist. 5:393-404, 2000.
    • Dietary fat may not play and important role in the development of cancer. Instead, positive energy balance and physical inactivity as contributors to weight gain may increase the risk of cancer. Other dietary factors such as folic acid may reduce the risk of cancer. [abstract]
  9. Zock, PL. Dietary fats and cancer. Curr Opin Lipid. 12:5-10. 2001.
    • Review examines the data from animal studies and epidemiological studies for evidence of a possible link between dietary fat and cancer. The author concludes that the relation between dietary fat and cancer is weak. [abstract]
Link to introduction page10/21/02